KTYS is an acronym that stands for Knoxville McGhee Tyson Airport. Located in Knoxville, Tennessee, it is the largest airport in the East Tennessee region and serves as a hub for Allegiant Air, American Airlines, and Delta Air Lines. KTYS is also home to the Knoxville Aviation Museum, which houses a variety of aircraft and artifacts from the history of aviation. KTYS is the primary airport for travelers in the Knoxville area, offering both domestic and international flights.